The G'MIC plug-in for GIMP proposes a set of various filters to apply on your images, including artistic effects, image denoising and enhancement algorithms, 3D renderers, etc.. It is a quite large plug-in, integrating a lot of different effects.
The wavelet denoise plugin is a tool to reduce noise in each channel of an image separately. The default colour space to do denoising is YCbCr which has the advantage that chroma noise can be reduced without affecting image details. Denoising in CIELAB (L*a*b*) or RGB is available as an option. The user interface allows colour mode and preview channel selection. The denoising threshold can be set for each colour channel independently.